Voltage Gated K+ Channel
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Contents |
More Specific Terms
- K+ voltage-gated channel subfamily KQT member 1; voltage-gated K+ channel subunit Kv7.1; IKs producing slow voltage-gated K+ channel subunit alpha KvLQT1; KQT-like 1 (KCNQ1, KCNA8, KCNA9, KVLQT1)
- voltage-gated K+ A channel (K+ channel IA , ISA, IA, A type K+ channel)
Function
- establish resting membrane potential
- modulate frequency & duration of action potential in neurons & muscle cells
Structure
- four alpha subunits form a functional K+ channel
- beta subunits are accessory (modulatory)
More General Terms
Additional Terms
References
- Kubo Y, Baldwin TJ, Jan YN, Jan LY. Primary structure and functional expression of a mouse inward rectifier potassium channel. Nature. 1993 Mar 11;362(6416):127-33. PMID: [1]
- Martens JR, Kwak YG, Tamkun MM. Modulation of Kv channel alpha/beta subunit interactions. Trends Cardiovasc Med. 1999 Nov;9(8):253-8. Review. PMID: [2]
- Chen X and Johnston D Properties of single voltgage-dependent K+ channels in dendrites of CA1 pyramidal neurones of rat hippocampus. J Physiol 2004, 559:187 PMID: [3]
