Urinary Alkalinization

From Anvita Health Wiki

Contents 1 Indications 2 Procedure 3 Management 4 More General Terms 5 Additional Terms 6 References

Indications

• salicylate toxicity
• hyperuricemia, tumor lysis syndrome
• cystinuria
• facilitates urinary excretion of acidic pharmaceuticals & toxins

• chlorpropamide
• diflunisal,
• fluoride
• methotrexate
• phenobarbital
• salicylate ( herbicide)
• mecoprop ( herbicide)

Procedure

• administration of intravenous sodium bicarbonate to produce urine with a pH >= 7.5

Management

• increased intake of fruits & vegetables
• decreased protein intake

More General Terms

• clinical procedure

Additional Terms

• urinary acidification

References

1. Proudfoot AT, Krenzelok EP, Vale JA Position Paper on urine alkalinization J Toxicol Clin Toxicol. 2004;42(1):1-26. Review. PMID: [1]
2. Goldfarb DS Urinary alkalinization Cysteinuria Support Network [2]
3. Chander B and Obligado S Tumor Lysis Syndrome and the Role of Urinary Alkalinization Clinical Correlations, The NYU Internal Medicine Blog [3]

urinary alkalinization (alkaline diuresis)