Ubiquitin Conjugating Enzyme 7 Interacting Protein 4

From Anvita Health Wiki

Contents 1 Function 2 Structure 3 Compartment 4 More General Terms 5 Internet Database 6 References

Function

• E3 ubiquitin-protein ligase that accepts ubiquitin from E2 ubiquitin-conjugating enzymes UBE2L3 & UBE2L6 in the form of a thioester & then directly transfers the ubiquitin to targeted substrates ( putative)
• protein modification; protein ubiquitination
• interacts with UBE2L3

Structure

• belongs to the RBR family, RNF144 subfamily
• contains 1 IBR-type Zn+2 finger
• contains 2 RING-type Zn+2 fingers
• lacks the His residue in the RING-type domain 2 that is one of the conserved features of the family

Compartment

• membrane ( potential)

More General Terms

• ubiquitin conjugating enzyme 7 interacting protein
• ring finger protein
• E3 ubiquitin ligase
• membrane protein

Internet Database

Entrez gene: 9781
Kegg: [1]
Prosite: [2]
Prosite: [3]
UniProt: [4]

References

UniProt [5]

E3 ubiquitin-protein ligase RNF144A; RING finger protein 144A; ubiquitin-conjugating enzyme 7-interacting protein 4; UbcM4-interacting protein 4 (RNF144A, KIAA0161, RNF144, UBCE7IP4)