Toxidrome

From Anvita Health Wiki

Contents 1 Introduction 2 Clinical-manifestations 3 More General Terms 4 References

Introduction

• A group of signs & symptoms that consistently result from particular drugs, toxins, intoxicants.

• Toxidromes include:

• sympathomimetic (Sym)
• antimuscarinic (AM)
• cholinergic (Chol)
• sedative/ hypnotic (S/H)
• opioid

Clinical-manifestations

*                      opioid     AM     Chol     Sym      S/H 
* pulse                   d       i        d       i        d 
* blood pressure          d       i        v       i        d 
* respirations            d       v        v       i        d 
* temperature             d       i        d       i        d 
* bowel sounds            d       d        i       -        -

• d = decreased, i = increased, v = variable, - = no change

<br>  
*               opioid       AM       Chol       Sym        S/H <br> 
* skin           sweaty     dry,red,  sweaty     sweaty     normal 
*                           hot . 
* mental       depressed    agitated  depressed  agitated  depressed 
* status                    delirium             delirium 
*                           seizures             seizures <br> 
* pupils        miosis      mydriasis   miosis   mydriasis   miosis 
*                                                            normal 

• Other:
• Opiates: track marks
• antimuscarinic: urinary retention
• cholinergic: fasciculations, weakness, bronchospasm, bronchorrhea
• d = decreased, i = increased, v = variable, - = no change

More General Terms

• toxicology

References

Daubert GP, Emergency Medicine, University of California, Davis

toxidrome (toxic syndrome)