Toremifene

From Anvita Health Wiki

Contents 1 Indications 2 Pharmacokinetics 3 Drug-interactions 4 More General Terms 5 Additional Terms 6 Internet Database 7 References

Indications

• metastatic breast cancer in postmenopausal women with estrogen receptor-positive or receptor unknown tumors

Pharmacokinetics

• metabolized in the liver by cyt P450 3A4
  

• elimination via liver

Drug-interactions

• any drug that inhibits cyt P450 3A4 may increase levels of toremifene
• any drug that induces cyt P450 3A4 may diminish levels of toremifene

More General Terms

• antineoplastic agent (chemotherapeutic agent)

Additional Terms

• breast cancer
• cytochrome P450 3A4 (cytochrome P450 C3, nifedipine oxidase, P450-PCN1, NF-25, CYP3A4)

Internet Database

PubChem: 3005573
PubChem: 3005572
PubChem: 5516
PubChem: 56008

References

1. Kaiser Permanente Northern California, Drug update, 9/2000
2. Prescriber's Letter 13(3): 2006 Cytochrome P450 drug interactions Detail-Document#: [1] (subscription needed) [2]

toremifene (Fareston)