Temsirolimus
From Anvita Health Wiki
Contents |
Indications
Dosage
Adverse-effects
- allergic reactions, angioedema
- weakness, fatigue
- edema
- headache
- dysgeusia
- sore mouth or throat
- loss of appetite, weight loss
- nausea/vomiting
- constipation, diarrhea, bloody stools
- urinary frequency, dysuria, hematuria, oliguria
- back pain, myalgia, arthralgia
- epistaxis
- changes in fingernails or toenails
- dry skin
- tachycardia
- acne
- insomnia
- depression
- dyspnea, tachypnea
- dysphagia
- flushing
- chest pain
- dizziness, fainting
- new or worsening abdominal pain
- blurred vision
- dysarthria
- confusion
- focal neurologic deficit
Mechanism-of-action
- kinase inhibitor, inhibits mTOR
- leads to cell cycle arrest in G1 phase
- inhibits tumor angiogenesis by reducing synthesis of VEGF
More General Terms
References
