Tat Binding Protein 1

From Anvita Health Wiki

Contents 1 Function 2 Structure 3 Compartment 4 More General Terms 5 Internet Database 6 References

Function

• regulatory ATPase of 26S proteasome
• confers ATP dependency & substrate specificity to the 26S proteasome
• may form a heterodimer with a related family member
• interacts with PAAF1
• interacts with HIV-1 Tat, suppresses Tat-mediated transactivation

Structure

• belongs to the AAA ATPase family

Compartment

• cytoplasm, nucleus

More General Terms

• adenosine triphosphatase (ATPase)
• transcription factor (TF)
• phosphoprotein

Internet Database

Kegg: [1]
OMIM: 186852
Prosite: [2]
UniProt: [3]

References

UniProt [4]

TAT-binding protein-1; 26S protease regulatory subunit 6A; proteasome subunit P50 (TBP1, PSMC3)