Sweat Chloride

From Anvita Health Wiki

Contents 1 Indications 2 Clinical-significance 3 Increases 4 Notes 5 More General Terms 6 Additional Terms 7 References

Indications

• sweat chloride using pilocarpine iontophoresis is the gold standard for diagnosis of cystic fibrosis ( CF).

Clinical-significance

• > 80 meq/L is abnormal in adults
• > 60 meq/L is abnormal in children
• abnormal results on at least 2 tests is necessary for diagnosis of cystic fibrosis
• other conditions associated with high sweat [Na+] & [[[Cl-]]]

• smoking
• chronic bronchitis
• malnutrition
• hereditary nephrogenic diabetes insipidus
• adrenal insufficiency
• ectodermal dysplasia

Increases

• cystic fibrosis

Notes

• sweat sodium is generally measured along with chloride as confirmation of the measured chloride value.

More General Terms

• special chemistry test

Additional Terms

• cystic fibrosis (CF, mucoviscidosis)
• pilocarpine iontophoresis

References

Mayo Internal Medicine Board Review, 1998-99, Prakash UBS (ed) Lippincott-Raven, Philadelphia, 1998, pg 745

chloride (Cl-) & sodium (Na+) in sweat