Squamous Cell Carcinoma Of The Anus

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Contents 1 Etiology 2 Pathology 3 Complications 4 Management 5 More General Terms 6 Additional Terms 7 References

Etiology

• human papillomavirus

• same forms linked to SCC of the cervix & penis

• increased incidence in patients with AIDS

Pathology

• slow progression or anal intraepithelial neoplasia to squamous cell carcinoma of the anus [2]

Complications

• 
  
• disease interaction(s) of cancer with Alzheimer's disease

Management

• screening not recommended [2]

More General Terms

• anorectal disease
• squamous cell carcinoma (SCC)

Additional Terms

• anus
• papillomavirus
• rectal carcinoma

References

1. Medical Knowledge Self Assessment Program (MKSAP) 11, American College of Physicians, Philadelphia 1998
2. Machalek DA et al Anal human papillomavirus infection and associated neoplastic lesions in men who have sex with men: a systematic review and meta-analysis The Lancet Oncology, Early Online Publication, 23 March 2012 <PubMed> PMID: [1] <Internet> [2]
   - Wentzensen N Screening for anal cancer: endpoints needed The Lancet Oncology, Early Online Publication, 23 March 2012 <PubMed> PMID: [3] <Internet> [4]
3. Anal Cancer: NIH Institute and Center Resources [5]
4. National Guideline Clearinghouse Anal cancer. American College of Radiology ngc-guideline: [6]
   - Management of squamous cell cancer of the anal canal: guideline recommendations. Program in Evidence-based Care ngc-guideline: [7]

squamous cell carcinoma (SCC) of the anus