Sodium In Serum
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Contents |
Indications
- assessing acid-base balance, water balance, water intoxication, & dehydration
- evaluation of hyponatremia
- evaluation of hypernatremia
Reference-interval
- Male & Female: 136 - 146 mmol/L
Principle
- See sodium (Na+) in body fluid
Clinical-significance
- Sodium is the primary extracellular cation. The amount of sodium in the body is a reflection of the balance between sodium intake & output.
Increases
- see hypernatremia
- pharmaceutical agents:
-
- androgens, Rauwolfia alkaloids, corticosteroids, mannitol, methyldopa, oxyphenbutazone, phenylbutazone
Decreases
- see hyponatremia
- pharmaceutical agents:
- in vivo effects
Specimen
- No special patient preparation is required.
- Serum preparation: collect whole blood & allow to clot according to manufacturer's instructions. Specimens are collected in a red top vacutainer by venipuncture & should be separated immediately from the cells after collection.
- Heparin may be used as an anticoagulant for plasma specimens, although sodium heparin will increase the measured sodium value by approximately 0.5 mmol/L. Do not use potassium oxalate/ sodium fluoride anticoagulants.
- Minimum sample size 0.5 milliliter: with an optimum size of 1.0 milliliters or larger.
More General Terms
Additional Terms
References
- Kodak Ektachem 700 Analyzer Operator's Manual, Kodak Clinical Products, Rochester, New York.
- Kodak Ektachem Clinical Slide Package Insert, Kodak Clinical Products, Rochester, New York.
- Kodak Ektachem Clinical Training Manual, Kodak Clinical Products, Rochester, New York.
- Tietz, N. W.: Electrolytes, in Textbook of Clinical Chemistry, Philadelphia, W. B. Saunders Co., p. 1845, 1986.
