Sodium Fluoride

From Anvita Health Wiki

Contents 1 Introduction 2 Indications 3 Contraindications 4 Dosage 5 Pharmacokinetics 6 Adverse-effects 7 Drug-interactions 8 More General Terms 9 Additional Terms 10 Internet Database 11 References

Introduction

• Tradename: Luride.

Indications

• prevention of dental caries

Contraindications

• pregnancy-category :value ?
• safety-in-lactation :value ?

Dosage

• 1-2 mg QD
• Luride: 1 mg or 8 drops PO QD.

• 2.2 mg tab = 1 mg of fluoride
• 0.25, 0.5, 1.0, 1.125 mg/drop.

Pharmacokinetics

• elimination :route kidney

Adverse-effects

• uncommon (< 1%)

• rash, GI upset, nausea/vomiting, mucous membrane ulceration, tremors, stomach cramps

• other

• headache
• weakness

Drug-interactions

• magnesium, aluminum & calcium decrease absorption of fluoride

More General Terms

• salt
• dental agent

Additional Terms

• fluoride (F-)
• Na+

Internet Database

PubChem: 24339
PubChem: 5235
PubChem: 518582
PubChem: 14916

References

1. Drug Information & Medication Formulary, Veterans Affairs, Central California Health Care System, 1st ed., Ravnan et al eds, 1998 - not on National VA formulary
2. The Pharmacological Basis of Therapeutics, 9th ed. Gilman et al, eds. Permagon Press/McGraw Hill, 1996
3. Kaiser Permanente Northern California Regional Drug Formulary, 1998
4. Professionally applied topical fluoride Evidence-based clinical recommendations American Dental Association (ADA) [1]
5. National Guideline Clearinghouse Professionally applied topical fluoride. Evidence-based clinical recommendations. American Dental Association ngc-guideline: [2]
   - Guidelines for the use of fluorides. New Zealand Guidelines Group ngc-guideline: [3]

sodium fluoride (NaF, Luride)