Signal Sequence Receptor

From Anvita Health Wiki

Contents 1 Function 2 Structure 3 Compartment 4 More General Terms 5 References

Function

• binding of Ca+2 to the endoplasmic reticulum ( ER) membrane & thus regulate retention of ER resident proteins

Structure

• heterotetramer of TRAP-alpha, TRAP-beta, TRAP-delta & TRAP-gamma

Compartment

• endoplasmic reticulum membrane

More General Terms

• phosphoprotein
• glycoprotein
• membrane protein
• multisubunit protein

References

1. Ou WJ et al Association of folding intermediates of glycoproteins with calnexin during protein maturation. Nature 364:771 1993 PMID: [1]
2. UniProt [2] UniProt [3] UniProt [4] UniProt [5]

endoplasmic reticulum signal sequence receptor (SSR, translocon-associated protein, TRAP)