Serine/threonine Kinase 11 Interacting Protein

From Anvita Health Wiki

Contents 1 Function 2 Structure 3 Compartment 4 Alternative-splicing 5 Notes 6 More General Terms 7 Internet Database 8 References

Function

• may regulate STK11 function by controlling its subcellular localization
• found in a ternary complex composed of STK11, STK11IP & SMAD4
• interacts with STK11 & SMAD4
• phosphorylated

Structure

• belongs to the STK11IP family
• contains 6 LRR repeats ( leucine-rich repeats)

Compartment

• cytoplasm
• some cells show granular or punctate expression
• colocalizes with STK11 & SMAD4 in granular or punctate structures

Alternative-splicing

• named isoforms=2

Notes

• uncertain whether Met-1 or Met-12 is the initiator

More General Terms

• uncharacterized protein

Internet Database

OMIM: 607172
UniProt: [1]

References

UniProt [2]

Serine/threonine kinase 11-interacting protein (LKB1-interacting protein 1, STK11IP, KIAA1898, LIP1, LKB1IP, STK11IP1)