Second Generation Antidepressant

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Contents 1 More Specific Terms 2 Introduction 3 More General Terms 4 References

More Specific Terms

• atypical antidepressant
• selective serotonin reuptake inhibitor (SSRI)
• trazodone (Desyrel, Pragmazone, Oleptro)

Introduction

• All second generation antidpressants have similar efficacy [1]
  

• Also see antidepressant or specific agent
  
• Includes:

• bupropion
• citalopram
• duloxetine
• escitalopram
• fluoxetine
• fluvoxamine
• mirtazapine
• nefazodone
• paroxetine
• sertraline
• trazodone
• venlafaxine

More General Terms

• antidepressant

References

1. Gartlehner G et al Comparative Benefits and Harms of Second-Generation Antidepressants for Treating Major Depressive Disorder: An Updated Meta-analysis Annals of Internal Medicine, December 6, 2011, 155(11):772-785 <PubMed> PMID: [1] <Internet> [2]
2. Qaseem A et al. Using second-generation antidepressants to treat depressive disorders: A clinical practice guideline from the American College of Physicians. Ann Intern Med 2008 Nov 18; 149:725. PMID: &dopt=Abstract
   - Gartlehner G et al. Comparative benefits and harms of second-generation antidepressants: Background paper for the American College of Physicians. Ann Intern Med 2008 Nov 18; 149:734. PMID: [3]

second generation antidepressant