Rock Protein

From Anvita Health Wiki

Contents 1 More Specific Terms 2 Introduction 3 Function 4 More General Terms 5 References

More Specific Terms

• rho-associated coiled-coil-containing protein kinase 1; p160ROCK; ROK-beta; Rho-associated protein kinase 1 (ROCK1)
• Rho-associated protein kinase 2; Rho kinase 2; Rho-associated, coiled-coil-containing protein kinase 2; p164 ROCK-2 (ROCK2, KIAA0619)

Introduction

• two isoforms: ROCK1 & ROCK2.

Function

• downstream effector of Rho proteins
• role in cytokeletal assembly & reorganization

More General Terms

• serine/threonine kinase

References

Zhao Z, Rivkees SA.  Rho-associated kinases play a role in endocardial cell  differentiation and migration. Dev Biol. 2004 Nov 1;275(1):183-91. PMID: [1]

rho-associated kinase ROCK