Reticulocyte Count

From Anvita Health Wiki

Contents 1 Reference-interval 2 Clinical-significance 3 Increases 4 Decreases 5 More General Terms 6 Additional Terms 7 References

Reference-interval

• 0.5-1.5%
• 25,000-75,000/ uL

Clinical-significance

• reticulocyte count is an indication of the erythropoietic response to anemia
• it is useful for classifying anemia as hypoplastic vs blood loss or hemolysis
• corrected measures are often applied based upon an expected increase in reticulocyte production in response to anemia
• 1st correction = reticulocyte index

• (Hgb patient/Hgb control) x reticulocyte count

Increases

• increased levels > 100,000/ uL

• hemolytic anemia
• hemorrhage (3-4 days later)
• replacement of hematic factor
• sickle cell anemia
• post splenectomy
• pregnancy
• polycythemia

Decreases

• hypoplastic anemias

• pernicious anemia
• folic acid deficiency
• adrenocortical hypofunction
• aplastic anemia
• radiation therapy
• anterior pituitary hypofunction
• chronic infection
• cirrhosis
• malignancy

More General Terms

• clinical hematology test

Additional Terms

• reticulocyte

References

1. Medical Knowledge Self Assessment Program (MKSAP) 11, American College of Physicians, Philadelphia 1998
2. Mosby's Diagnostic and Laboratory Test Reference, 9th edition, Pagana DS and Pagana TJ editors, Mosby, Elsevier, St. Louis, 2009

reticulocyte count