Ras Association Domain Containing Protein 4

From Anvita Health Wiki

Contents 1 Function 2 Structure 3 Alternative-splicing 4 Expression 5 More General Terms 6 Internet Database 7 References

Function

• potential tumor suppressor
• may act as a KRAS effector protein
• may promote apoptosis & cell cycle arrest
• interacts directly with activated KRAS ( GTP-dependent)

Structure

• contains 1 Ras-associating domain
• contains 1 SARAH domain

Alternative-splicing

• named isoforms=4

Expression

• widely expressed
• frequently down-regulated in tumor cell lines

More General Terms

• Ras association domain-containing protein (RASSF)

Internet Database

UniProt: [1]

References

UniProt [2]

Ras association domain-containing protein 4 (RASSF4)