Protocol For Oral Desensitization To Beta Lactam Antibiotics

From Anvita Health Wiki

Procedure

*                                    cumulative 
* time (min)            dose (mg)     dose (mg) 
*   0                   0.05           0.05 
*  15                   0.1            0.15 
*  30                   0.2            0.35 
*  45                   0.4            0.35 
*  60                   0.8            0.75 
*  75                   1.6            1.55 
*  90                   3.2            3.15 
* 105                   6.0            6.35 
* 120                  12.0           24.35 
* 135                  24.0           48.35 
* 150                  50.0           98.35 
* 165                 100.0          198.35 
* 180                 200.0          398.35 
* 195                 400.0          798.35

• After completion, observe patient for 15 minutes. If no problems, administer 1 g of same agent intravenously.
• The drug suspension 0.5-50 mg/mL is diluted in 30 mL of water for ingestion.

More General Terms

• clinical procedure
• protocol

References

Medical Knowledge Self Assessment Program (MKSAP) 11, American College of Physicians, Philadelphia 1998

protocol for oral desensitization to beta lactam antibiotics