Proquad

From Anvita Health Wiki

Contents 1 Indications 2 Contraindications 3 Adverse-effects 4 Mechanism-of-action 5 More General Terms 6 Additional Terms 7 References

Indications

• immunization of children 4-12* years of age
• may be used if 2nd dose of MMR is to be administered

Contraindications

• infants 1-2 years of age*

Adverse-effects

• febrile seizures* [3]

• * CDC recommends that MMR vaccine be given separate from varicella vaccine at 1-2 years of age due to risk of febrile seizures
• * at 4-6 years of age the risk of febrile seizures has resolved [4]

Mechanism-of-action

• attenuated live virus vaccine that combines measles, mumps, rubella & varicella viruses

More General Terms

• live virus vaccine

Additional Terms

• measles, mumps & rubella combined vaccine (MMR)

References

1. Monthly Prescribing Reference [1]
2. Shinefield H et al, Evaluation of quadrivalent measles, mumps, rubella and varicella vaccine in healthy children Pediatric Infect Dis J 2005; 24:665 PMID: [2]
3. Marin M, Broder KR, Temte JL, Snider DE, Seward JF, Centers for Disease Control and Prevention (CDC). Use of combination measles, mumps, rubella, and varicella vaccine: recommendations of the Advisory Committee on Immunization Practices (ACIP). MMWR Recomm Rep 2010 May 7;59(RR-3):1-12. PMID: [3]
4. Klein NP et al Measles-Containing Vaccines and Febrile Seizures in Children Age 4 to 6 Years Pediatrics April 2, 2012 <PubMed> PMID: [4] <Internet> [5]
5. National Guideline Clearinghouse
   - 1) General recommendations on immunization: recommendations of the Advisory Committee on Immunization Practices (ACIP).
6. Update: recommendations from the Advisory Committee on Immunization Practices (ACIP) regarding administration of combination MMRV vaccine. ngc-guideline: [6]
   - 1) Prevention of varicella: recommendations of the Advisory Committee on Immunization Practices (ACIP).
7. Update: recommendations from the Advisory Committee on Immunization Practices (ACIP) regarding administration of combination MMRV vaccine. ngc-guideline: [7]
   - Use of combination measles, mumps, rubella, and varicella vaccine: recommendations of the Advisory Committee on Immunization Practices. Centers for Disease Control and Prevention (CDC) ngc-guideline: [8]

Proquad (measles, mumps, rubella [MMR] plus varicella viruses live, MMRV)