Predisposition To Infection

From Anvita Health Wiki

Contents 1 More Specific Terms 2 Introduction 3 Additional Terms 4 References

More Specific Terms

• susceptibility to mycobacterial disease

Introduction

• Risk factors predisposing to patients
• neutropenia:

• especially lymphoma patients after chemotherapy

• altered cellular immunity
• humoral immunity dysfunction
• alteration in local defenses

• breakdown of skin

• trauma
• vasculitis
• malignancy: head & neck ( squamous cell carcinoma)
• bacterial pathogens

• Staphylococcus aureus
• Streptococcus pyogenes
• Pseudomonas aeruginosa ( burns)

• compromise in mucosal barrier ( mucositis)

• Streptococcus mitis

• occlusion of orifices: ureters, bile duct, colon

• malignancy: renal, ovarian, biliary, metastatic
• urinary tract infections & septicemia
• gram negative bacteria

• lymph node dissection

• cellulitis due to Staphylococcus & Streptococcus

• splenectomy
• indwelling devices

• endotracheal tube
• central venous catheter
• foley catheter

• metabolic acidosis

• associated conditions

• diabetes mellitus
• acute myelocytic leukemia

• common pathogens

• bacteria

• Pseudomonas aeruginosa (malignant external otitis)

• fungi: Zygomycetes ( mucormycosis)

• hyperalimentation

• associated conditions

• trauma
• abdominal surgery

• common pathogens

• bacteria

• coagulase-negative Staphylococcus
• Staphylococcus aureus

• fungi

• Candida
• Malassezia furfur

• intravenous drug abuse
• cirrhosis of the liver

Additional Terms

• cirrhosis
• immunodeficiency; immunodeficiency syndrome
• intravenous drug abuse (IVDA, injection drug use, IDU)
• neutropenia
• splenectomy

References

1. Medical Knowledge Self Assessment Program (MKSAP) 11, American College of Physicians, Philadelphia 1998
2. Harrison's Principles of Internal Medicine, 14th ed. Fauci et al (eds), McGraw-Hill Inc. NY, 1998, pg 537

factors predisposing to infection