Poliovirus Vaccine Live

From Anvita Health Wiki

Contents 1 Indications 2 Contraindications 3 Dosage 4 Drug-interactions 5 More General Terms 6 Additional Terms 7 References

Indications

• active immunization against poliovirus

Contraindications

• persistent vomiting or diarrhea
• allergy to sorbitol, streptomycin or neomycin
• hypersensitivity to inactivated poliovirus vaccine

• Caution:

• the vaccine will not modify or prevent exsisting or incubating poliomyelitis

• pregnancy-category C
• safety in lactation ?

Dosage

• Infants:

• 0.5 mL dose at 2, 4 & 18 months of age
• optional dose at 6 months where poliovirus is endemic

• Older children, adolescents & adults:

• two 0.5 mL doses 8 weeks apart
• 3rd dose 6-12 months after 2nd dose
• reinforcing dose of 0.5 mL should be given before entry to school in children who have received 3rd primary dose before their 4th birthday Oral: mixture of type 1, 2 & 3 viruses growth in monkey kidney tissue, 0.5 mL Adverse reactions:

• all serious adverse reactions must be reported to the the Vaccine Adverse Event Reporting System (800-822-7967)

Drug-interactions

• may temporarily suppress tuberculin skin reactivity (4-6 weeks)
• immunosuppressive agents
• immune globulin

More General Terms

• vaccine

Additional Terms

• polio virus

References

Kaiser Permanente Northern California Regional Drug  Formulary, 1998

polio virus vaccine,live, trivalent, oral (Orimune, OPV, Sabin vaccine, TOPV)