Plasminogen Activator Inhibitor 1 Genotyping

From Anvita Health Wiki

Contents 1 Clinical-significance 2 Specimen 3 More General Terms 4 References

Clinical-significance

• plasminogen activator inhibitor-1

• major inhibitor of fibrinolysis
• when increased, fibrinolytic activity is diminished with increased risk of

• arterial thrombosis
• venous thrombosis

• increased activity is an independent risk factor for

• coronary artery disease
• ischemic stroke
• venous thrombosis
• osteonecrosis

Specimen

• whole blood

More General Terms

• molecular diagnostic test

References

1. Molecular Diagnostics Laboratory [1]
2. Vaughan DE. PAI-1 and atherothrombosis. J Thromb Haemost. 2005 Aug;3(8):1879-83. PMID: [2]

plasminogen activator inhibitor-1 genotyping