Photosensitivity

From Anvita Health Wiki

Contents 1 More Specific Terms 2 Etiology 3 Laboratory 4 Diagnostic-procedures 5 Management 6 More General Terms 7 Additional Terms 8 References

More Specific Terms

• drug-induced photosensitivity (photoallergic reaction)

Etiology

• idiopathic

• actinic prurigo
• chronic actinic dermatitis
• hydroa vacciniforme
• polymorphous light eruption
• solar urticaria
• hydroa aestivale
• actinic reticuloid

• metabolic

• porphyrias

• hereditary coproporphyria
• porphyria cutanea tarda
• variegate porphyria
• congenital erythropoietic porphyria
• erythropoietic protoporphyria

• Bloom's syndrome
• Cockayne's syndrome
• Rothmand-Thompson syndrome
• Xeroderma pigmentosum
• phenylketonuria
• albinism
• Hartnup disease
• kwashiorkor
• pellagra
• carcinoid syndrome
• pseudoporphyria

• neoplastic

• basal cell carcinoma
• actinic keratosis

• degenerative

• photoaging

• photoaggravated

• lupus erythematosus

• systemic lupus erythematosus
• subacute cutaneous lupus erythematosus

• dermatomyositis
• pemphigus foliaceus
• Herpes simplex
• lichen planus actinicus
• acne vulgaris (aestivale)
• transient acantholytic dermatosis

• drug induced (see drugs that may cause photosensitivity)

Laboratory

• complete blood count ( CBC)
• serum chemistries

• liver function tests
• renal function tests

• serology

• antinuclear antibody ( ANA)
• anti-SSA
• anti-SSB

• erythrocyte chemistries

• uroporphyrin
• coproporphyrin
• protoporphyrin

• urine

• uroporphyrin
• coproporphyrin
• aminolevulinic acid
• porphobilinogen

• feces

• uroporphyrin
• coproporphyrin
• protoporphyrin

• skin biopsy

• light microscopy
• direct immunofluorescence microscopy

Diagnostic-procedures

• Phototesting
• patch & photopatch testing
• assessment of DNA repair

Management

• avoid sunlight
• sunblock (Mexoryl may help)
• antihistamines for pruritis
• topical glucocorticoids [4]

More General Terms

• sign/symptom

Additional Terms

• photosensitizing agent (photosensitizer)
• phototherapy

References

1. Color Atlas & Synopsis of Clinical Dermatology, Common & Serious Diseases, 3rd ed, Fitzpatrick et al, McGraw Hill, NY, 1997, pg 983-89
2. Harrison's Principles of Internal Medicine, 14th ed. Fauci et al (eds), McGraw-Hill Inc. NY, 1998, pg 331
3. Prescriber's Letter 12(8): 2005 Drug-Induced Photosensitivity Detail-Document#: [1] (subscription needed) [2]
4. Medical Knowledge Self Assessment Program (MKSAP) 15, American College of Physicians, Philadelphia 2009

photosensitivity