Phenylbutyrate

From Anvita Health Wiki

Contents 1 Indications 2 Dosage 3 Adverse-effects 4 More General Terms 5 References

Indications

• used to treat urea cycle disorder by facilitating clearance of ammonia

Dosage

• oral dose based on size: < 20 grams (40 tablets)/day
• given in divided doses 3-6 times/day with meals
  

•  : 500 mg

Adverse-effects

• common

• change in frequency of breathing
• irregular menstruation
• low back pain
• stomach pain
• mood or mental changes
• myalgia, muscle twitching
• nausea, vomiting
• nervousness or restlessness
• pedal edema
• dysgeusia
• fatigue or weakness

• less common

• fever, chills
• arthralgia
• sore throat
• unusual bleeding or bruising

• rare

• seizures
• dizziness
• dryness of the mouth
• palpitations
• hypertension
• increased thirst
• irritability
• muscle cramps
• rectal bleeding
• swelling of the face
• unusual weight gain
• weak pulse

More General Terms

• carboxylate
• metabolic agent (metabolic modifier)

References

1. Drugs.com [1]

phenylbutyrate (Buphenyl)