Peroxin 6
From Anvita Health Wiki
Contents |
Function
- role in peroxisome biosynthesis
- required for stability of the PTS1 receptor
- anchored by PEX26 to peroxisome membranes, possibly to form heteromeric AAA ATPase complexes
- required for the import of proteins into peroxisomes
- interacts directly with PEX26 & PEX1
- mediates the indirect interaction between PEX1 & PEX26
Structure
- belongs to the AAA ATPase family
Compartment
- cytoplasm, peroxisome membrane
- associated with peroxisomal membranes
Pathology
- defects in PEX6 are the cause of peroxisome biogenesis disorder complementation group 4
- defects in PEX6 are a cause of Zellweger syndrome
More General Terms
Internet Database
UniProt: [1]
Entrez gene: 5190
Kegg: [2]
OMIM: 214100
OMIM: 601498
OMIM: 601539
Prosite: [3]
References
