Pcr/southern Blot For Alpha Thalassemia

From Anvita Health Wiki

Contents 1 Indications 2 Clinical-significance 3 Specimen 4 More General Terms 5 Additional Terms 6 References

Indications

• alpha thalassemia

Clinical-significance

• diagnosis of alpha thalassemia trait requires quantitative PCR to detect reduced number of alpha globin genes

Specimen

• whole blood ( ACD or EDTA)
• amniocytes
• chorionic villi
• store whole blood at 4 degrees C
• store at -20 degrees C or below if nucleic acids cannot be extracted immediately

More General Terms

• molecular diagnostic test

Additional Terms

• alpha thalassemia

References

Clinical Guide to Laboratory Tests, 3rd ed. Teitz ed.,  W.B. Saunders, 1995

PCR/southern blot for alpha thalassemia