Pcr/southern Blot/ish For Follicular Lymphoma

From Anvita Health Wiki

Contents 1 Genetics 2 Indications 3 Specimen 4 More General Terms 5 Additional Terms 6 References

Genetics

• associated genetic aberrations:

• chromosomal translocation t14q32:18q21 ( bcl-2 proto oncogene)

Indications

• follicular lymphoma

Specimen

• tumor tissue
• whole blood ( ACD or EDTA)
• store body fluid at 4 degrees C
• store tissue at -20 degrees C or below

More General Terms

• molecular diagnostic test

Additional Terms

• bcl-2 proto-oncogene
• chromosomal translocation t14q32:t18q21 (follicular lymphoma)
• follicular B-cell lymphoma (follicular center lymphoma, chronic lymphatic leukemia type 2)

References

Clinical Guide to Laboratory Tests, 3rd ed. Teitz ed.,  W.B. Saunders, 1995

PCR/southern blot/in-situ hybridization for follicular lymphoma