Pcr/southern Blot/ish For Chronic Myelogenous Leukemia

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Contents 1 Genetics 2 Indications 3 Specimen 4 More General Terms 5 Additional Terms 6 References

Genetics

• associated genetic aberrations:

• chromosomal translocation t9q34:22q11 ( Philadelphia chromosome)

Indications

• chronic myelogenous leukemia

Specimen

• bone marrow
• whole blood ( ACD or EDTA)
• store body fluid at 4 degrees C
• store tissue at -20 degrees C or below

More General Terms

• molecular diagnostic test

Additional Terms

• chromosomal translocation t9q34:22q11 (Philadelphia chromosome; bcr/abl)
• chronic myeloid leukemia (CML, granulocytic leukemia)

References

Clinical Guide to Laboratory Tests, 3rd ed. Teitz ed.,  W.B. Saunders, 1995

PCR/southern blot/in-situ hybridization for chronic myelogenous leukemia