Nuvaring

From Anvita Health Wiki

Contents 1 Introduction 2 Dosage 3 Adverse-effects 4 Mechanism-of-action 5 Notes 6 More General Terms 7 Internet Database 8 References

Introduction

• A vaginal contraceptive ring. FDA approved 2001

Dosage

• leave ring in for 3 weeks; remove for 4th week of cycle
• if ring is expelled, may be washed & resinserted
• use back-up contraception if ring has been removed > 3 hours
• continue backup contraception until ring has been in place 7 days

Adverse-effects

• 2-fold increased risk relative to oral contraceptives [4]
  
• drug adverse effects of hormonal contraception

Mechanism-of-action

• small vaginal ring
• releases etonogestrel + ethinyl estradiol

Notes

• lowest estrogen exposure vs patch, oral contraceptive [3]

More General Terms

• contraceptive
• ethinyl estradiol/etonogestrel

Internet Database

PubChem: 208920

References

1. Prescriber's Letter 9(2):S1 2002
2. Prescriber's Letter 9(6):32 2002
3. van den Heuvel MW, van Bragt AJ, Alnabawy AK, Kaptein MC. Comparison of ethinylestradiol pharmacokinetics in three hormonal contraceptive formulations: the vaginal ring, the transdermal patch and an oral contraceptive. Contraception. 2005 Sep;72(3):168-74. PMID: [1]
4. Lidegaard O et al Venous thrombosis in users of non-oral hormonal contraception: follow-up study, Denmark 2001-10 BMJ 2012;344:e2990 Not yet indexed in PubMed [2]
5. Organon. [3]

NuvaRing (etonogestrel, ethinyl estradiol)