Nucleoplasmin

From Anvita Health Wiki

Contents 1 More Specific Terms 2 Introduction 3 Function 4 Structure 5 More General Terms 6 References

More Specific Terms

• nucleoplasmin 1 (numatrin, nucleophosmin, nucleolar phosphoprotein B23)
• nucleoplasmin 2 (NPM2)
• nucleoplasmin 3 (NPM3)

Introduction

• One of at least 3 nuclear proteins than interact with histones

Function

• binds to histone H2A & histone H2B
• dissociates from histone H2A & histone H2B upon formation of nucleosome

Structure

• acidic protein

More General Terms

• DNA-binding protein
• adenosine triphosphatase (ATPase)

References

1. Molecular Cell Biology (2nd ed) Darnell J; Lodish H & Baltimore D (eds), Scientific American Books, WH Freeman, NY 1990, pg 333
2. Laskey RA et al The role of nucleoplasmin in chromatin assembly and disassembly Philos. Trans. R. Soc. Lond. B. Biol. Sci. 1993, 339268 PMID 8098530
3. Wikipedia: Nucleoplasmin ATPase [1]

nucleoplasmin