Nucleolar Organizing Region

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Contents 1 Introduction 2 More General Terms 3 Additional Terms 4 References

Introduction

• Regions where the nucleus reforms after mitosis. Clusters of ribosomal RNA genes may be found. Antigens recognized by autoantibodies in scleroderma may be found within this region including Scl-70, fibrillarin, RNA polymerase I & NOR-90.

More General Terms

• organelle

Additional Terms

• nucleolar transcription factor 1; autoantigen NOR-90; upstream-binding factor 1; UBF-1 (UBTF, UBF, UBF1)
• nucleolus
• scleroderma (systemic sclerosis)

References

Clinical Diagnosis & Management by Laboratory Methods, 19th edition, J.B. Henry (ed), W.B. Saunders Co., Philadelphia, PA. 1996, pg 1019

nucleolar organizing region