Nilotinib

From Anvita Health Wiki

Contents 1 Indications 2 Pharmacokinetics 3 Monitor 4 Drug-interactions 5 More General Terms 6 References

Indications

• FDA-approved for imatinib resistant CML

Pharmacokinetics

• metabolized by CYP3A4

Monitor

• liver function tests periodically

Drug-interactions

• induces & inhibits CYP2C8 & CYP2C9
• inhibits CYP2D6
• inhibits CYP3A4

More General Terms

• antineoplastic agent (chemotherapeutic agent)

References

- Prescriber's Letter 17(7): 2010 Recommended Lab Monitoring for Common Medications Liver Function Test Scheduling Detail-Document#: [1] (subscription needed) [2] nilotinib (Tasigna)