Multiple Sleep Latency Test

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Introduction

• Sleep is measured over night.
• The following day, repeated measurements of sleep latency (time to onset of sleep) is measured at 2 hour intervals under standardized conditions
• In narcolepsy, a decreased mean sleep latency with at least 2 sleep onset REM-periods is observed

• mean latency to sleep in narcolepsy patients is 5 minutes
• mean latency to sleep in normal individuals > 10 minutes

• EEG, EKG & EOG ( electro-oculogram) are monitored

More General Terms

• clinical procedure

References

1. Saunders Manual of Medical Practice, Rakel (ed), WB Saunders, Philadelphia, 1996, pg 1038
2. Harrison's Principles of Internal Medicine, 12th ed. Wilson et al (eds), McGraw-Hill Inc. NY, 1991, pg 215

multiple sleep latency test (MSLT)