Monobenzone

From Anvita Health Wiki

Contents 1 Indications 2 Contraindications 3 Dosage 4 Adverse-effects 5 Mechanism-of-action 6 More General Terms 7 Internet Database 8 References

Indications

• topical treatment of vitiligo

Contraindications

• freckling
• hyperpigmentation caused by photosensitization following use of certain perfumes
• melasma ( chloasma) of pregnancy
• hyperpigmentation resulting from inflammation of the skin
• cafe-au-lait spots
• pigmented nevi
• malignant melanoma
• pigmentation resulting from pigments other than melanin (e.g.: bile, silver, or artificial pigments)

Dosage

• applied topically BID- TID to permanently depigmented normal skin surrounding vitiliginous lesions in patients with disseminated (>50% of body surface area)
  

• Cream: 20%

Adverse-effects

• allergic reaction, angioedema
• can can destruction of melanocytes & permanent depigmentation

Mechanism-of-action

• increases excretion of melanin from melanocytes

More General Terms

• ether
• phenol
• dermatologic agent

Internet Database

PubChem: 7638

References

1. Benoquin [1]
2. MedicineNet.com [2]

monobenzone (Benoquin)