Molybdenum Cofactor Sulfurase

From Anvita Health Wiki

Contents 1 Function 2 Pathology 3 More General Terms 4 Internet Database 5 References

Function

• sulfurates molybdenum cofactor
• sulfation of molybdenum is essential for xanthine dehydrogenase & aldehyde oxidase in which molybdenum cofactor is liganded by 1 oxygen & 1 sulfur atom in active form
  

• Cofactor: pyridoxal phosphate

Pathology

• defects in MOCOS are the cause of xanthinuria type 2

More General Terms

• lyase
• phosphoprotein

Internet Database

OMIM: 603592
Prosite: [1]
UniProt: [2]

References

UniProt [3]

molybdenum cofactor sulfurase (MoCo sulfurase, MOS, HMCS, MOCOS)