Mitochondrial Import Inner Membrane Translocase Subunit Tim22

From Anvita Health Wiki

Contents 1 Function 2 Structure 3 Compartment 4 More General Terms 5 Internet Database 6 References

Function

• essential core component of the TIM22 complex
• in the TIM22 complex, it constitutes the voltage-activated & signal-gated channel
• forms a twin- pore translocase that uses the membrane potential as external driving force in 2 voltage-dependent steps
• interacts directly with TIMM9, TIMM10/TIM10A & FXC1/ TIM10B

Structure

• belongs to the Tim17/Tim22/ Tim23 family

Compartment

• mitochondrial inner membrane

More General Terms

• protein subunit
• transmembrane 3 protein
• mitochondrial membrane protein

Internet Database

Kegg: [1]
OMIM: 607251
UniProt: [2]

References

UniProt [3]

mitochondrial import inner membrane translocase subunit TIM22 (testis-expressed sequence 4, TIMM22, TEX4, TIM22)