Mitochondrial Carnitine/acylcarnitine Carrier Protein

From Anvita Health Wiki

Contents 1 Function 2 Structure 3 Compartment 4 Pathology 5 More General Terms 6 Internet Database 7 References

Function

• mediates transport of acylcarnitines of different length across the mitochondrial inner membrane from cytosol to mitochondrial matrix for their oxidation by the mitochondrial fatty acid-oxidation pathway

Structure

• belongs to the mitochondrial carrier family
• contains 3 solcar repeats

Compartment

• mitochondrial inner membrane

Pathology

• defects in SLC25A20 are the cause of carnitine-acylcarnitine translocase deficiency

More General Terms

• transmembrane 6 protein
• symporter
• glycoprotein
• solute carrier family 20 (SLC20, SLC20A)
• mitochondrial protein

Internet Database

Kegg: [1]
OMIM: 212138
Prosite: [2]
UniProt: [3]

References

1. UniProt [4]
2. GeneReviews [5]

mitochondrial carnitine/acylcarnitine carrier protein; carnitine/acylcarnitine translocase; CAC; solute carrier family 25 member 20 (SLC25A20, CAC, CACT)