Miglustat

From Anvita Health Wiki

Contents 1 Introduction 2 Indications 3 Adverse-effects 4 Mechanism-of-action 5 More General Terms 6 Internet Database 7 References

Introduction

• Tradename: Acetlion ( FDA approved 2003)

Indications

• Gaucher disease

• patients who cannot receive enzyme therapy ( FDA)

Adverse-effects

• GI distress, peripheral neuropathy, weight loss

Mechanism-of-action

• glucosylceramide synthase inhibitor

More General Terms

• enzyme inhibitor
• metabolic agent (metabolic modifier)

Internet Database

PubChem: 51634

References

1. Prescriber's Letter 11(2):suppl 2004
2. Zimmerman, Ari

miglustat (Acetlion, Zavesca)