Microsomal Glutathione S Transferase 2

From Anvita Health Wiki

Contents 1 Function 2 Structure 3 Compartment 4 Expression 5 More General Terms 6 Internet Database 7 References

Function

• can catalyze the production of LTC4 from LTA4 & reduced glutathione
• can catalyze the conjugation of 1-chloro-2,4-dinitrobenzene with reduced glutathione
  

• RX + glutathione = HX + R-S- glutathione
  

Structure

• homotrimer
• belongs to the MAPEG family

Compartment

• membrane ( potential)

Expression

• liver, spleen, skeletal muscle, heart, adrenals, pancreas, prostate, testis, fetal liver, & fetal spleen
• very low expression in lung, brain, placenta & bone marrow

More General Terms

• microsomal glutathione S-transferase

Internet Database

Kegg: [1]
OMIM: 601733
Prosite: [2]
UniProt: [3]

References

UniProt [4]

microsomal glutathione S-transferase 2 (microsomal GST- 2, microsomal GST-II, MGST2, GST2)