Membrane Protein Mlc1

From Anvita Health Wiki

Contents 1 Function 2 Compartment 3 Expression 4 Pathology 5 More General Terms 6 Internet Database 7 References

Function

• may be a transporter
• may act as a non-selective neuronal cation channel

Compartment

• membrane

Expression

• expressed in brain
• highest levels in the amygdala, caudate nucleus, thalamus, hippocampus

Pathology

• defects in MLC1 are a cause of megalencephalic leukoencephalopathy with subcortical cysts
• defects in MLC1 are a cause of periodic catatonia

More General Terms

• carrier protein (transporter)
• ion channel
• transmembrane 6 protein

Internet Database

OMIM: 604004
OMIM: 605908
UniProt: [1]

References

UniProt [2]

membrane protein MLC1 (MLC1, KIAA0027, WKL1)