Melkersson Rosenthal Syndrome

From Anvita Health Wiki

Contents 1 Etiology 2 Epidemiology 3 Clinical-manifestations 4 Differential-diagnosis 5 Management 6 More General Terms 7 References

Etiology

• idiopathic
• may be a genetic predispositione
• may be manifestation of Crohn's disease or sarcoidosis

Epidemiology

• rare
• onset is in childhood or early adolescence

Clinical-manifestations

• recurring facial paralysis

• days to years may separate attacks

• edema of the face & lips (usually upper lip)

• swelling may persist & increase between attacks
• eventually becoming permanent

• development of folds & furrows in the tongue
• lip may become hard, cracked, & fissured with reddish-brown discoloration

Differential-diagnosis

• Crohn's disease
• sarcoidosis

Management

• treatment is symptomatic
• nonsteroidal anti-inflammatory drugs ( NSAIDs)
• corticosteroids to reduce swelling
• antibiotics
• immunosuppressants
• surgery

• relieve pressure on facial nerve & its branches,
• reduce swollen tissue
• effectiveness has not been established

• massage & electrical stimulation may also be prescribed
• prognosis

• may recur intermittently
• may become chronic disorder

• work up for Crohn's disease & sarcoidosis

More General Terms

• facial disorder/injury/anomaly
• neurologic disease

References

NINDS Melkersson-Rosenthal Syndrome Information Page [1]

Melkersson-Rosenthal syndrome