Magnesium Citrate

From Anvita Health Wiki

Contents 1 More Specific Terms 2 Indications 3 Contraindications 4 Dosage 5 Pharmacokinetics 6 Adverse-effects 7 Mechanism-of-action 8 More General Terms 9 Additional Terms 10 Internet Database 11 References

More Specific Terms

• calcium & magnesium citrate

Indications

• relief of constipation

Contraindications

• pregnancy-category :value +
• safety-in-lactation :value ?

Dosage

• 4 mL/kg PO up to 300 mL [1]
• 4-8 oz once; may be repeated once [2]

• Liquid: 10 oz bottle.

Pharmacokinetics

• onset of bowel relief is in 3-6 hours
• elimination :route kidney)

Adverse-effects

• repeated or frequent administration may cause

• hypermagnesemia
• electrolyte imbalance
• dehydration

Mechanism-of-action

• saline laxative
• Mg+2 may stimulate release of cholecystokinin, which increases motor & sensory action in the GI tract

More General Terms

• laxative
• Mg+2
• citrate (citric acid)
• salt

Additional Terms

• calcium & magnesium citrate

Internet Database

PubChem: 24511
PubChem: 107785

References

1. The Pharmacological Basis of Therapeutics, 9th ed. Gilman et al, eds. Permagon Press/McGraw Hill, 1996
2. Drug Information & Medication Formulary, Veterans Affairs, Central California Health Care System, 1st ed., Ravnan et al eds, 1998

magnesium citrate (citrate of magnesia)