Lung Cancer

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Contents 1 More Specific Terms 2 Introduction 3 Pathology 4 Clinical-manifestations 5 Diagnostic-procedures 6 Radiology 7 Complications 8 Management 9 More General Terms 10 Additional Terms 11 Internet Database 12 References

More Specific Terms

• carcinoma of the lung
• lung cancer pathogensis - genetic & pathways
• Pancoast tumor (superior pulmonary sulcus tumor)

Introduction

• Primary lung cancers are predominantly lung carcinomas.

Pathology

• small cell carcinoma (18%)

• occurs almost exclusively in smokers
• invariably metastatic on presentation

• squamous cell carcinoma (29%)

• tends to occur more centrally

• adenocarcinoma (32%)

• most common type in non- smokers
• tends to occur more peripherally

• bronchoalveolar carcinoma ( adenocarcinoma, 3%)

• low-grade carcinoma frequently presenting as patchy infiltrate

• large cell carcinoma (9%)
• bronchial carcinoid (1%)
• mesothelioma
• mucoepidermoid carcinoma (0.1%)
• adenoid cystic carcinoma (< 0.1%)
• metastases

• lymph nodes (83% local, 29% distant)
• liver (73%)
• ipsilateral or contralateral lung (8%)
• bone (56%)
• brain (37%)
• adrenal (35%)
• kidney (16%)

Clinical-manifestations

• (see lung carcinoma)

Diagnostic-procedures

• (see lung carcinoma)

Radiology

• (see lung carcinoma)

Complications

• 
  
• disease interaction(s) of cancer with Alzheimer's disease

Management

• (see lung carcinoma)

More General Terms

• malignant neoplasm (cancer)
• lung neoplasm

Additional Terms

• lung cancer pathogensis - genetic & pathways
• lung neoplasm
• mediastinal neoplasm
• PCR/southern blot for lung cancer
• pleural neoplasm
• pulmonary metastases
• screening for lung cancer
• staging of lung cancer

Internet Database

OMIM: 211980

References

1. Saunders Manual of Medical Practice, Rakel (ed), WB Saunders, Philadelphia, 1996, pg 30
2. Mayo Internal Medicine Board Review, 1998-99, Prakash UBS (ed) Lippincott-Raven, Philadelphia, 1998, pg 671-673, 766-69
3. Harrison's Principles of Internal Medicine, 14th ed. Fauci et al (eds), McGraw-Hill Inc. NY, 1998, pg 521, 553
4. Pathology of the Lungs. Corrin. Churchill-Livingstone 2000
5. National Guideline Clearinghouse
   - Lung cancer. In: Suspected cancer in primary care: guidelines for investigation, referral and reducing ethnic disparities New Zealand Guidelines Group ngc-guideline: [1]
   - Lung cancer. The diagnosis and treatment of lung cancer. National Collaborating Centre for Cancer ngc-guideline: [2]

lung cancer