Liposarcoma

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Contents 1 More Specific Terms 2 Epidemiology 3 Microscopic-pathology 4 Genetics 5 Complications 6 More General Terms 7 References

More Specific Terms

• dedifferentiated liposarcoma
• myxoid liposarcoma
• pleomorphic liposarcoma
• round cell liposarcoma
• well-differentiated liposarcoma; atypical lipomatous tumor; sclerosing liposarcoma; inflammatory liposarcoma; spindle cell liposarcoma

Epidemiology

• ~20% of adulthood sarcomas [2]

Microscopic-pathology

• Identification of lipoblasts which range from:
• primitive mesenchymal cells with only tiny lipid droplets
• intermediate form with scanty cytoplasm, multiple variably sized lipid droplets and small nucleus centrally or peripherally located
• signet-ring like cells with most of cytoplasm occupied by single large fat droplet Histologic subtypes:
• well-differentiated liposarcoma (atypical lipoma/ atypical lipomatous tumor)

• lipoma like
• sclerosing
• inflammatory
• spindle cell
• dedifferentiated

• myxoid liposarcoma

• round cell liposarcoma

• pleomorphic liposarcoma

Genetics

• implicated genes PRUNE

Complications

• 
  
• disease interaction(s) of cancer with Alzheimer's disease

More General Terms

• sarcoma
• adipose tissue neoplasm

References

1. Enzinger & Weiss. Soft Tissue Tumors. Mosby. 3rd ed. 1995
2. Gebhard et al. Am J Surgical Pathology 26:601-16, 2002

liposarcoma