Ligand Gated Ion Channel Zn+2 Activated 1

From Anvita Health Wiki

Contents 1 Function 2 Structure 3 Compartment 4 Alternative-splicing 5 Expression 6 Notes 7 More General Terms 8 Internet Database 9 References

Function

• Zn+2-activated ligand-gated ion channel

Structure

• glycosylated
• belongs to the ligand-gated ionic channel (TC 1.A.9) family

Compartment

• cell membrane

Alternative-splicing

• named isoforms=3

Expression

• detected in pancreas, brain, liver, placenta, trachea, kidney, spinal cord, stomach & fetal brain
• in the adult brain, expression is detected in the hippocampus, striatum, amygdala & thalamus

Notes

• It is uncertain whether Met-1 or Met-2 is the initiator

More General Terms

• glycoprotein
• ion channel
• evolutionary divergent protein

Internet Database

Kegg: [1]
Prosite: [2]
UniProt: [3]

References

UniProt [4]

ligand-gated ion channel Zn+2-activated 1 (ligand-gated ion-channel receptor L2, LGICZ1, L2, LGICZ, ZAC)