Leukemia
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Contents |
More Specific Terms
- acute leukemia
- chronic leukemia
- leukemia cutis
- lymphoid leukemia
- meningeal leukemia
- myeloid leukemia
- plasmacytic leukemia
- therapy-related leukemia
Genetics
Clinical-manifestations
-
- skin - petechia, purpura
- gums - gingival hypertrophy, oozing
- mucous membranes
- hematuria
- melena
- skin - pyoderma gangrenosum
- throat
- sinus
- gums
- respiratory tract
- urinary tract
- CNS symptoms
- bone pain
- gastrointestinal ( GI) symptoms
Laboratory
- complete blood count ( CBC) with differential
- peripheral blood smear
- Chemistry profile
- leukemia panel by flow cytometry
- coagulation studies
-
- fibrinogen
- fibrin-split products
- blood cultures when appropriate
- histochemical stains
- cytochemical stains
- immunological stains
- phenotyping
- flow cytometry
- karyotypic analysis
- routine CSF analysis
- cytology
- cultures
Complications
Differential-diagnosis
- Marrow failure of AML/ ALL vs aplastic anemia
- marrow infiltration with nonhematopoietic tumors
- children
- adults
- presence of lymphadenopathy or splenomegaly
-
- iatrogenic hypersensitivity
- potentially malignant entities
Management
- varies with type of leukemia
More General Terms
Additional Terms
References
- Saunders Manual of Medical Practice, Rakel (ed), WB Saunders, Philadelphia, 1996, pg 594
- Leukemia: NIH Institute and Center Resources [1]
