Lanthanum Carbonate

From Anvita Health Wiki

Contents 1 Introduction 2 Indications 3 Dosage 4 Adverse-effects 5 Mechanism-of-action 6 More General Terms 7 Internet Database 8 References

Introduction

• Tradename: Fosrenol

Indications

• reduction of serum phosphorus in patient with end-stage renal disease Contrindications:

• Pregnancy category: C

Dosage

• start 760-1500 mg QD in divided doses
• increase as needed at 2 week intvervals in 750 mg increments
• most patients require* 1500-3000 mg QD

• Tabs: 250 & 500 mg (elemental lanthunum)
• * requirement assessed by serum phosphate < 6 mg/dL

Adverse-effects

• nausea/vomiting 10%
• dialysis graft occlusion 8%
• abdominal pain 8%

Mechanism-of-action

• La+2-containing phosphate-binder

More General Terms

• metabolic agent (metabolic modifier)
• salt

Internet Database

PubChem: 176168

References

1. Prescriber's Letter 11(12): 2004 New Drug: Lanthanum Carbonate (Fosrenol) Detail-Document#: [1] (subscription needed) [2]
2. url>http://www.fosrenol.com</url>

lanthanum carbonate (La2[CO3]3, Fosrenol)