L Plastin

From Anvita Health Wiki

Contents 1 Function 2 Structure 3 Compartment 4 Expression 5 More General Terms 6 Internet Database 7 References

Function

• actin-binding protein found in intestinal microvilli, hair cell stereocilia, & fibroblast filopodia
• phosphorylated

Structure

• the N-terminus is blocked
• monomer
• contains 2 actin-binding domains
• contains 4 CH (calponin-homology) domains
• contains 2 EF-hand domains

Compartment

• cytoplasm

Expression

• restricted to spleen & other lymph node-containing organs
• expressed in neutrophils, monocytes, B lymphocytes, & myeloid cells

More General Terms

• plastin or fimbrin

Internet Database

UniProt: [1]
Entrez gene: 3936
Kegg: [2]
OMIM: 153430
Prosite: [3]
Prosite: [4]
Prosite: [5]
Prosite: [6]
Prosite: [7]

References

1. UniProt [8]
2. Atlas of Genetics & Cytogenetics in Oncology & Haematology [9]

plastin-2; L-plastin; lymphocyte cytosolic protein 1; LCP-1; LC64P (LCP1 PLS2)