K+ Channel Subfamily K Member 18

From Anvita Health Wiki

Contents 1 Function 2 Structure 3 Compartment 4 Expression 5 More General Terms 6 Internet Database 7 References

Function

• outward rectifying K+ channel
• produces rapidly activating outward rectifier K(+) currents
• may function as background K+ channel that sets the resting membrane potential
• inhibited by arachidonic acid & other naturally occurring unsaturated free fatty acids
• channel activity is enhanced by volatile anesthetics, including as isoflurane

Structure

• belongs to the two pore domain K+ channel (TC 1.A.1.8) family

Compartment

• membrane

Expression

• detected at low levels in spinal cord

More General Terms

• K+ channel subfamily K
• phosphoprotein
• glycoprotein
• transmembrane 6 protein

Internet Database

UniProt: [1]

References

UniProt [2]

K+ channel subfamily K member 18 (TWIK-related individual K+ channel, TWIK-related spinal cord K+ channel, KCNK18, TRESK, TRIK)