Inwardly Rectifying K+ Channel J12

From Anvita Health Wiki

Contents 1 Function 2 Structure 3 Compartment 4 More General Terms 5 Internet Database 6 References

Function

• inwardly rectifying K+ channel that probably participates in establishing action potential waveform & excitability of neuronal & muscle tissues
• can be blocked by extracellular Ba+2 & Cs+2
• association, via its PDZ-recognition domain, with LIN7A, LIN7B, LIN7C, DLG1, CASK & APBA1 plays a key role in its localization & trafficking ( putative)

Structure

• belongs to the inward rectifier-type K+ channel family

Compartment

• membrane

More General Terms

• inwardly-rectifying K+ channel subfamily J
• ATP-sensitive K+ channel (inwardly-rectifying K+ channel)
• phosphoprotein

Internet Database

UniProt: [1]
Entrez gene: 100131
Entrez gene: 100290
Entrez gene: 3768
Kegg: [2]
Kegg: [3]
Kegg: [4]
OMIM: 602323

References

UniProt [5]

ATP-sensitive inward rectifier K+ channel 12; K+ channel, inwardly rectifying subfamily J member 12; Inward rectifier K+ channel Kir2.2; Kir2.2v; IRK2 (KCNJ12, IRK2, KCNJN1)